ChemicalBook >> CAS DataBase List >>6-Chloroguanine
6-Chloroguanine
- CAS No.
- 10310-21-1
- Chemical Name:
- 6-Chloroguanine
- Synonyms
- 2-AMINO-6-CHLOROPURINE;6-Chloro-7H-purin-2-amine;6-CHLORO-2-AMINOPURINE;2-amino-6-chloro-purin;9H-PURIN-2-AMINE, 6-CHLORO-;2-AMINO-6-CHLOROPURINE (2A6ClP);AURORA KA-689;6-CHLOROGUANINE;TIMTEC-BB SBB003863;2-Amino-6-chloropuri
- CBNumber:
- CB4143631
- Molecular Formula:
- C5H4ClN5
- Molecular Weight:
- 169.57
- MDL Number:
- MFCD00075252
- MOL File:
- 10310-21-1.mol
- MSDS File:
- SDS
Last updated:2025-03-19 13:53:49
| Melting point | >300 °C (lit.) |
|---|---|
| Boiling point | 279.76°C (rough estimate) |
| Density | 1.4937 (rough estimate) |
| refractive index | 1.6110 (estimate) |
| storage temp. | 2-8°C |
| solubility | Solubility in 1mol/L NaOH |
| form | Powder |
| pka | 6.65±0.20(Predicted) |
| color | White to yellow |
| Water Solubility | 1.7 g/L (20 ºC) |
| BRN | 9626 |
| InChI | InChI=1S/C5H4ClN5/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H3,7,8,9,10,11) |
| InChIKey | RYYIULNRIVUMTQ-UHFFFAOYSA-N |
| SMILES | N1C2C(=NC(N)=NC=2Cl)NC=1 |
| CAS DataBase Reference | 10310-21-1(CAS DataBase Reference) |
| EWG's Food Scores | |
| FDA UNII | |
| EPA Substance Registry System |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P201-P202-P261-P264b-P271-P280i-P302+P352-P304+P340-P305+P351+P338-P308+P313-P332+P313-P362+P364-P403+P233-P501c | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UO7502000 | |||||||||
| F | 10 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
6-Chloroguanine price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2861 | Famciclovir Related Compound F pharmaceutical secondary standard, certified reference material | 10310-21-1 | 50MG | $485 | 2025-03-01 | Buy |
| Sigma-Aldrich | 109789 | 2-Amino-6-chloropurine ≥99% | 10310-21-1 | 1g | $26 | 2025-03-01 | Buy |
| Sigma-Aldrich | 109789 | 2-Amino-6-chloropurine ≥99% | 10310-21-1 | 5g | $31.2 | 2025-03-01 | Buy |
| TCI Chemical | A1407 | 2-Amino-6-chloropurine >98.0%(HPLC)(T) | 10310-21-1 | 1g | $34 | 2025-03-01 | Buy |
| TCI Chemical | A1407 | 2-Amino-6-chloropurine >98.0%(HPLC)(T) | 10310-21-1 | 5g | $101 | 2025-03-01 | Buy |
6-Chloroguanine Chemical Properties,Uses,Production
Description
6-Chloroguanine, also be known as 2-Amino-6-chloropurine may be used in the enzymatic synthesis of 2′-deoxyguanosine, 9-alkyl purines (R)and (S)-N(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases. It is also useful during the synthesis of guanine.Description
2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).Chemical Properties
white to light yellow crystal powderUses
2-Amino-6-chloropurine finds its uses in the enzymatic synthesis of 2?-deoxyguanosine, 9-alkyl purines and (R)- and (S)-N-(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases.Uses
2-Amino-6-chloropurine may be used:
- in the enzymatic synthesis of 2′-deoxyguanosine
- in the synthesis of 9-alkyl purines
- in the synthesis of (R)- and (S)-N-(2-phosphonomethoxypropyl) derivatives of purine and pyrimidine bases
Definition
ChEBI: 6-chloroguanine is an organochlorine compound that is 7H-purin-2-amine substituted by a chloro group at position 6. It is a member of 2-aminopurines and an organochlorine compound.General Description
2-Amino-6-chloropurine is a 6-substituted purine. Tautomeric purine forms of 2-amino-6-chloropurine were investigated by vibrational spectroscopy and quantum chemical method.Synthesis
Preparation of 2-amino-6-chloropurine:
Diacetyl guanine (8.0g, 0.034 moles), triethyimethylammonium chloride (15.45g, 0.102 moles), and triethylamine (4.74 mis, 0.034 moles) were heated together with stirring in acetonitrile (70mls) to 50°C. Phosphorus oxychioride (6.34 mis, 0.068 moles) was then added and stirring continued for 4 hours. The reaction mixture was cooled and then added to aqueous sodium hydroxide solution (20g in 300mls water). The reaction mixture was heated to 80°C for 2 hours and then the volume made up to 300 mis with water. The mixture was cooled to 25°C and the pH adjuster to 7 using 10% hydrochloric acid. The resulting slurry was stirred for fifteen minutes and the product filtered off and washed with water 30 mis and then dried at 80°C under vacuum to give a cream/off white coloured product, 2-amino-6-chioropurine 4.69 g (74.6% yield).
6-Chloroguanine Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
Global( 640)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou Measure Life Technology Co., LTD | +8613343730176 | 2924244016@qq.com | China | 83 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12416 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2504 | 58 |
| Henan Fengda Chemical Co., Ltd | +8613613820652 | info@fdachem.com | China | 4827 | 58 |
| airuikechemical co., ltd. | +undefined86-15315557071 | 15315557071@163.com | China | 395 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 14764 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21702 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
View Lastest Price from 6-Chloroguanine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-03-26 | 6-Chloroguanine
10310-21-1
|
US $0.00 / Kg/Drum | 100g/Bag | 99% | 100mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2025-03-19 | 2-Amino-6-chloropurine
10310-21-1
|
US $0.00-0.00 / g | 1g | 99.99% | 20 tons | airuikechemical co., ltd. | |
 |
2025-02-06 | 6-Chloroguanine
10310-21-1
|
US $0.00-0.00 / kg | 1kg | 98% | 500kg per month | Yunbio Tech Co.,Ltd. |
-
- 6-Chloroguanine
10310-21-1
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 2-Amino-6-chloropurine
10310-21-1
- US $0.00-0.00 / g
- 99.99%
- airuikechemical co., ltd.
-
- 6-Chloroguanine
10310-21-1
- US $0.00-0.00 / kg
- 98%
- Yunbio Tech Co.,Ltd.
10310-21-1(6-Chloroguanine)Related Search:
2-Amino-4-chloro-6-methoxypyrimidine
4,6-Dimethoxy-2-methylthiopyrimidine
2-Amino-4,6-dimethylpyrimidine
6-Chloroguanine
6-CHLOROGUANINE RIBOSIDE,6-Chloroguanine nucleoside,(-)-2-Amino-6-chloropurine riboside, 6-Chloroguanine riboside
9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine
8-CHLOROGUANINE,CHLOROGUANINE
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6-Chloropurine
1of4
Clofarabine Impurity 3
AURORA KA-689
2-amino-6-chloro-purin
2-AMINO-6-CHLOROPURINE
6-CHLORO-2-AMINOPURINE
6-CHLORO-9H-PURIN-2-YLAMINE
6-CHLOROGUANINE
6-Chloro-7H-purin-2-ylamine
TIMTEC-BB SBB003863
6-Chloro-2-purinamine
6-Chloro-7H-purine-2-amine
2-AMINO-6-CHLOROPURINE (2A6ClP)
2-Amino-6-chloropuri
6-chloro-9H-purin-2-amine(SALTDATA: FREE)
2-aMino-6-cyanopurine 2-AMino-9H-purine-6-carbonitrile
2-AMino-6-chlorpurin
FaMciclovir Related CoMpound F
2-AMino-6-chloropurine, 98+%
2 - aMino - 6 - chlorine purine
Famciclovir Related Compound F (25 mg) (2-Amino-6-chloropurine)
1H-Purin-2-amine, 6-chloro- (9CI)
2-Amino-6-chlorpurine
Purine, 2-amino-6-chloro-
6-chloro-1h-purin-2-amin
6-chloro-1h-purin-2-amine
FAMCICLOVIR INTERMEDIATES
9-(4-acetoxy-3-acetoxymethylbut-1-y)-2-amino-6-chloro purine
2-Amino-6-chloro-9H-purine
6-CHLOROGUANINE CRYSTALLINE
2-Amino-6-Chloropurine(6-Chloroguanine)
1H-Purin-2-amine, 6-chloro-
2-Amino-6-chloro-9H-purine 99%
9H-PURIN-2-AMINE, 6-CHLORO-
6-CHLOROGUANINE extrapure
6-Chloro-7H-purin-2-amine
4-Chloro-1,3,5,7-tetraaza-1H-indene-6-amine
2-Amino-6-chloropurine >
2-Amino-6-Chloro-Purin,>98%
Famciclovir USP RC F
6-Chloroguanine USP/EP/BP
Famciclovir Related Compound F (2-Amino-6-chloropurine) (1269141)
Famciclovir USP Related Compound F
2-Amino-6-c2-Amino-6-chloropurinehloropurine
Famciclovir Related Compound F (2-Amino-6-chloropurine)
10310-21-1
10310-21-2
233-686-7
C5H4CIN5
C5H4ClN2
Building Blocks
Halogenated Heterocycles
Heterocyclic Building Blocks
Purines
Biochemistry
Nucleobases and their analogs
Nucleosides, Nucleotides & Related Reagents
Nucleic acids
Bases & Related Reagents