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DIPHENYLCYCLOPROPENONE

CAS No.
886-38-4
Chemical Name:
DIPHENYLCYCLOPROPENONE
Synonyms
Diphencyprone;2,3-DIPHENYLCYCLOPROP-2-EN-1-ONE;2,3-DIPHENYL-2-CYCLOPROPEN-1-ONE;1,2-DIPHENYLCYCLOPROPEN-3-ONE;opropenone;RARECHEM AQ C3 0050;Diphencyclopropenone;α,β-Carbonylstilbene;iphenylcyclopropenone;DIPHENYLCYCLOPROPENONE
CBNumber:
CB2289953
Molecular Formula:
C15H10O
Molecular Weight:
206.24
MDL Number:
MFCD00001311
MOL File:
886-38-4.mol
MSDS File:
SDS
Last updated:2024-05-25 18:01:02

DIPHENYLCYCLOPROPENONE Properties

Melting point 118-122 °C (lit.)
Boiling point 305.09°C (rough estimate)
Density 1.232
refractive index 1.6324 (estimate)
storage temp. Store below +30°C.
solubility DMF:20.0(Max Conc. mg/mL);96.97(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);96.97(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);2.42(Max Conc. mM)
Ethanol:14.0(Max Conc. mg/mL);67.88(Max Conc. mM)
form Crystalline Powder
color Slightly pinkish-orange to beige
Merck 14,3308
BRN 608049
InChIKey HCIBTBXNLVOFER-UHFFFAOYSA-N
LogP 1.769 (est)
CAS DataBase Reference 886-38-4(CAS DataBase Reference)
EWG's Food Scores
FDA UNII
NCI Drug Dictionary

SAFETY

Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P362+P364
Hazard Codes  Xi
Risk Statements  38-43
Safety Statements  36/37
WGK Germany  3
HS Code  29142990
NFPA 704
0
0 0

DIPHENYLCYCLOPROPENONE price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20533 2,3-Diphenyl-2-cyclopropen-1-one for synthesis 886-38-4 1g $67.3 2025-03-01 Buy
Sigma-Aldrich 8.20533 2,3-Diphenyl-2-cyclopropen-1-one for synthesis 886-38-4 5G $249 2025-03-01 Buy
Sigma-Aldrich 177377 Diphenylcyclopropenone 98% 886-38-4 1g $76.9 2025-03-01 Buy
Sigma-Aldrich 177377 Diphenylcyclopropenone 98% 886-38-4 5g $226 2025-03-01 Buy
Sigma-Aldrich 8.20533 2,3-Diphenyl-2-cyclopropen-1-one for synthesis 886-38-4 500mg $39.4 2024-01-07 Buy
Product number Packaging Price Buy
8.20533 1g $67.3 Buy
8.20533 5G $249 Buy
177377 1g $76.9 Buy
177377 5g $226 Buy
8.20533 500mg $39.4 Buy

DIPHENYLCYCLOPROPENONE Chemical Properties,Uses,Production

Description

Diphencyprone (DCP) is a contact sensitizing agent. Pretreatment with DCP reduces symptom severity in a mouse model of experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (1-10) (MBP1-10). It enhances IL-10 production and antigen-specific IgG2a antibody responses and reduces anaphylaxis and asthma induced by ovalbumin in mice when administered during ovalbumin immunization at a concentration of 1% v/v. Topical administration of DCP increases intrafollicular CD4+ and CD8+ T cells, reduces upper dermal inflammation, and stimulates hair growth in the C3H/HeJ mouse model of alopecia areta. Formulations containing DCP have been used in the treatment of alopecia areta.

Description

Diphencyprone is a potent contact allergen responsible for occupational contact dermatitis in chemists and dermatological staff.

Chemical Properties

slightly pinkish-orange to beige crystalline

Uses

Diphenylcyclopropenone was used in topical immunotherapy.

Definition

ChEBI: A cyclopropenone compound having phenyl substituents at the 2- and 3-positions.

General Description

Diphenylcyclopropenone is a potent hapten. Its vibration frequency has been evaluated.

Contact allergens

Diphencyprone is a potent contact allergen used in topical immunotherapy to treat some severe alopecia areata. It is responsible for occupational contact dermatitis in chemists and dermatology department staff

Purification Methods

Crystallise it from cyclohexane. UV (MeCN): max 226, 282, 297nm. [Beilstein 17 IV 1736.]

DIPHENYLCYCLOPROPENONE Preparation Products And Raw materials

Global( 173)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21689 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Accela ChemBio Inc.
(+1)-858-699-3322 info@accelachem.com United States 19965 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8822 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
TopScience Biochemical
00852-68527855 info@itopbiochem.com China Hong Kong 902 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49391 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58

View Lastest Price from DIPHENYLCYCLOPROPENONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-02-18 DIPHENYLCYCLOPROPENONE
886-38-4
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Guanlang Biotechnology Co., Ltd.
trực tiếp đá gà hôm nayLiên kết đăng nhập 2020-07-06 DIPHENYLCYCLOPROPENONE
886-38-4
US $1.00 / kg 1kg 95%-99% 100kg Career Henan Chemical Co
Diphenylcyclopropenone 98% 2,3-Diphenyl-2-cyclopropen-1-one, 99% dry weight, may contain up to 5% water 2,3-Diphenyl-2-cyclopropen-1-one for synthesis RARECHEM AQ C3 0050 2,3-Diphenyl-2-cyclopropene-1-one 2,3-Diphenyl-cycloprop-2-enone 2,3-Diphenylcyclopropenone Cyclopropenone, 2,3-diphenyl- Cyclopropenone, diphenyl- 2-Cyclopropen-1-one, 2,3-diphenyl- DIPHENYLCYCLOPROPENONE 2,3-Diphenyl-2-cyclopropen-l-one 2,3-Diphenyl-2-cyclopropen-1-one, 99% (dry wt.), may contain up to 5% water 1,2-Diphenylcyclopropenone Diphencyclopropenone 1,2-Diphenylcyclopropene-3-one 2,3-Diphenylcyclopropa-2-ene-1-one α,β-Carbonylstilbene 2,3-Diphenyl-2-cyclopropen-1-one, 99% (dry wt.), may cont up to 5% water Diphenylcyclopropenone ,99% Diphenylcyclopropenone,98% DiphenylcyclopropenoneDiphencyproneDPC Diphenylcyclopropenone - Pharmaceutical 2,3-DIPHENYL-2-CYCLOPROPEN-1-ONE FOR SYN opropenone iphenylcyclopropenone 1,2-DIPHENYLCYCLOPROPEN-3-ONE 2,3-DIPHENYL-2-CYCLOPROPEN-1-ONE 2,3-DIPHENYLCYCLOPROP-2-EN-1-ONE Diphencyprone Diphenylcyclopropenon, (DCP, DPCP) 886-38-4 Carbonyl Compounds C15 to C38 Building Blocks Ketones Organic Building Blocks C15 to C38 Carbonyl Compounds Ketones Building Blocks C15 to C38 Carbonyl Compounds Chemical Synthesis Organic Building Blocks
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