ChemicalBook >> CAS DataBase List >>Sesamin
Sesamin
- CAS No.
- 607-80-7
- Chemical Name:
- Sesamin
- Synonyms
- L-Sesamin;FAGAROL;SesameP.E.;SezaMin;SESAMIN;Fsesamin;d-Sesamin;NSC 36403;AI3-00811;SESAMIN(P)
- CBNumber:
- CB5783674
- Molecular Formula:
- C20H18O6
- Molecular Weight:
- 354.35
- MDL Number:
- MFCD00216134
- MOL File:
- 607-80-7.mol
- MSDS File:
- SDS
Last updated:2024-08-31 09:08:39
| Melting point | 121.0 to 125.0 °C |
|---|---|
| Boiling point | 504.4±50.0 °C(Predicted) |
| Density | 1.385±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (>25 mg/ml) |
| form | crystalline |
| color | White |
| Merck | 14,8470 |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChIKey | PEYUIKBAABKQKQ-AFHBHXEDSA-N |
| LogP | 4.064 (est) |
| FDA UNII |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
Sesamin price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 59867 | Sesamin analytical standard | 607-80-7 | 10mg | $229 | 2025-03-01 | Buy |
| Sigma-Aldrich | SMB00705 | Sesamin ≥98% (HPLC) | 607-80-7 | 10MG | $221 | 2024-06-20 | Buy |
| Sigma-Aldrich | SMB00705 | Sesamin ≥98% (HPLC) | 607-80-7 | 50MG | $815 | 2024-06-20 | Buy |
| Sigma-Aldrich | S9314 | Sesamin ≥95%, crystalline | 607-80-7 | 5mg | $436 | 2023-05-15 | Buy |
| TCI Chemical | S0495 | Sesamin >98.0%(GC) | 607-80-7 | 100mg | $362 | 2025-03-01 | Buy |
Sesamin Chemical Properties,Uses,Production
Description
Sesamin (607-80-7) is a natural product derived from sesame seeds with anticancer1, antioxidant2, anti-inflammatory/immunomodulatory3, and antidiabetic4,5 effects. It also displayed effects on cholesterol and fatty acid metabolism.6? Sesamin was recently found to inhibit bacterial L-tryptophan indole lyase (Ki = 7 μM).7 This enzyme reacts with dietary tryptophan to produce the uremic toxin indoxyl sulfate which exacerbates chronic kidney disease.Chemical Properties
White powderUses
Sesamin has been used:
- as a lignan to study its effects on the osteoblastic differentiation of rat bone marrow stromal cells (BMSCs)
- as a standard for the isolation of sesamin from sesame oil
- as an enterolignan to study its effects on the proliferation of estrogen-receptor (ER)-positive human breast cancer MCF-7 cells
Uses
A lignan isolated from the bark of Fagara plants and from sesame oil. Studies show that it has has multiple functions such as cholesterol-lowering and anti-hypertensive activities. It induces the expr ession of the gene for aldehyde dehydrogenase, an alcohol-metabolizing enzyme suggesting it regulates the metabolism of lipids, xenobiotics, and alcohol at the mRNA level.Definition
ChEBI: A lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR
General Description
Sesamin is a fat-soluble furfuran lignan present in Sesamum indicum?L seeds.
Biochem/physiol Actions
Non-competitive Δ5-desaturase inhibitor.References
Majdalawieh et al. (2017) A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum); Eur.? J. Pharmacol.?815 512 Kiso (2004) Antioxidative role of sesamin, a functional lignan in sesame seed, and its effect on lipid- and alcohol-metabolism in the liver: a DNA microarray study; Biofactors 21 191 Majdalawieh et al. (2021) Immunomodulatory and anti-inflammatory effects of sesamin: mechanisms of action and future directions; Crit.? Rev. Food Sci. Nutr.?5 1 Shahi et al. (2017) Effect of Sesamin Supplementation on Glycemic Status, Inflammatory Markers, and Adiponectin Levels in Patients with Type 2 Diabetes Mellitus; J. Diet. Suppl.?14 65 Farbood et al. (2019) Sesamin: A promising protective agent against diabetes-associated cognitive decline in rats; Life Sci. 230 169 Majdalawieh et al. (2020) Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: a comprehensive review; Eur. J. Pharmacol. 173417 Oikawa et al. (2022) (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis; Biochem. Biophys. Res. Commun.?590 158Sesamin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 389)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 270 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9342 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Shaanxi Yikanglong Biotechnology Co., Ltd. | 17791478691 | yklbiotech@163.com | CHINA | 296 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from Sesamin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-07 | Sesamin
607-80-7
|
US $0.00-0.00 / kg | 20kg | 99% | 200000 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2025-04-28 | Sesamin powder
607-80-7
|
US $0.00-0.00 / g | 1g | 98% | 2000 | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2024-07-29 | Sesamin
607-80-7
|
US $0.00-0.00 / kg | 1kg | 0.99 | 50000kg | Hebei Kingfiner Technology Development Co.Ltd |
-
- Sesamin
607-80-7
- US $0.00-0.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Sesamin powder
607-80-7
- US $0.00-0.00 / g
- 98%
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Sesamin
607-80-7
- US $0.00-0.00 / kg
- 0.99
- Hebei Kingfiner Technology Development Co.Ltd
607-80-7(Sesamin)Related Search:
[1S-(1BETA,3ALPHA-BETA,4BETA,6ALPHA-BETA)]-5,5'-(TETRAHYDRO-1H,3H-FURO[3,4-C]FURAN-1,4-DIYL)BIS-1,3-BENZODIOXOLE
Sesamine70%
SESAMIN(P)
SESAMIN(RG)
1,3-Benzodioxole,5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-,[1S-(1α,3aα,4α, 6aα)]-
1,3-Benzodioxole, 5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, [1S-(1a,3aa,4a,6aa)]-
Tetrahydro-1,4-bis[3,4-(methylenedioxy)phenyl]-1H,3H-furo[3,4-c]furan
(+)-5,5'-[(1S,3aβ,4S,6aβ)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]-bis-1,3-benzodioxole
(+)-5,5'-[(1S,3aβ,4β,6aβ)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(1,3-benzodioxole)
d-Sesamin
Pseudocubebin
SesaMin(Fagarol)
NSC 36403
SezaMin
(1S,3aR,4S,6aR)-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole
(1S,3aR,4S,6aR)-Tetrahydro-1,4-bis[3,4-(Methylenedioxy)phenyl]-1H,3H-Furo[3,4-c]furan
[1S-(1α,3aα,4α,6aα)]-5,5'-(Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-1,3-benzodioxole
(+)-SESAMIN
SESAMIN
SesaMin, froM SesaMuM indicuM
1,3-Benzodioxole,5,5'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis-, (1S,3aR,4S,6aR)-
Fsesamin
Sesamin, >=98%
Sesamin, 98%, from Sesamum indicum
Sesamin>
Sesamin USP/EP/BP
Jujube powder
Sesame Extract, Sesamin
5-[(3S,3aR,6S,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-1,3-benzodioxole
(1S,3aR,4S,6aR)-1,4-Bis(benzo[d][1,3]dioxol-5-yl)hexahydrofuro[3,4-c]furan
Sesamin (Fagarol, Fsesamin)
Sesamin, ≥95%
TIANFU-CHEM -Sesamin
(+)-sesamin
3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-ol
SesameP.E.
FAGAROL
L-Sesamin
Sesamin powder
Sesame Extract (Sesamin 90%)
Natural Sesamin Powder
Abametapir Impurity 28
AI3-00811
607-80-7
C20H15O5
C20H18O6
BioChemical
Biochemicals and Reagents
D to K
Enzyme Inhibitors by Enzyme
Enzyme Inhibitors
Enzymes, Inhibitors, and Substrates
D5-Desaturase
Heterocycles
Intermediates & Fine Chemicals
Pharmaceuticals
D5-DesaturaseArachidonic Acid Cascade
D to