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OXOMEMAZINE

CAS No.
3689-50-7
Chemical Name:
OXOMEMAZINE
Synonyms
Imakol;6847 RP;6487 RP;Dysedon;RP-6847;Doxergan;Dosegran;6847 R.P.;Oxomemazin;OXOEMAZINE
CBNumber:
CB1236273
Molecular Formula:
C18H22N2O2S
Molecular Weight:
330.44
MDL Number:
MFCD00868197
MOL File:
3689-50-7.mol
MSDS File:
SDS
Last updated:2024-05-21 10:59:17

OXOMEMAZINE Properties

Melting point 115°
Boiling point 492.4±34.0 °C(Predicted)
Density 1.1453 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Store at -20°C
solubility ≥ 33mg/mL in DMSO
pka 9.31±0.28(Predicted)
FDA UNII
ATC code

SAFETY

Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
GHS06
Signal word  Danger
Hazard statements  H330-H311-H301
Precautionary statements  P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
Toxicity LD50 oral in mouse: 140mg/kg

OXOMEMAZINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC O860005 (±)-Oxomemazine 3689-50-7 1g $920 2022-12-16 Buy
American Custom Chemicals Corporation API0009875 OXOMEMAZINE 95.00% 3689-50-7 1G $892.5 2022-12-16 Buy
ChemScene CS-0131898 Oxomemazine 3689-50-7 10mg $60 2022-12-16 Buy
American Custom Chemicals Corporation API0009875 OXOMEMAZINE 95.00% 3689-50-7 5MG $502.11 2022-12-16 Buy
Crysdot CD11134460 Oxomemazine 97% 3689-50-7 1g $680 2022-12-16 Buy
Product number Packaging Price Buy
O860005 1g $920 Buy
API0009875 1G $892.5 Buy
CS-0131898 10mg $60 Buy
API0009875 5MG $502.11 Buy
CD11134460 1g $680 Buy

OXOMEMAZINE Chemical Properties,Uses,Production

Originator

Doxergan,Specia,France,1964

Uses

(±)-Oxomemazine, is a phenothiazine-type antihistamines, that has also shown antibacterial activity against Mycobacterium tuberculosis.

Definition

ChEBI: Oxomemazine is a member of phenothiazines.

Manufacturing Process

Phenothiazine is reacted with 3-dimethylamino-2-methylpropyl chloride in the presence of sodium amide to give 3-(10-phenthiazinyl)-2-methyl-1dimethylaminopropane. 11.9 g of of this intermediate is dissolved with agitation in glacial acetic acid (120 cc). Pure sulfuric acid (d = 1.83; 0.5 cc) is added and a mixture of glacial acetic acid (10 cc) and hydrogen peroxide (8.5 cc of a solution containing 38 g of hydrogen peroxide in 100 cc) is then run in over 20 minutes. The temperature rises from 25°C to 35°C and is then kept at 60°C for 18 hours. The mixture is cooled and water (150 cc) is added and, with cooling, aqueous sodium hydroxide (d = 1.33; 220 cc). The resulting mixture is extracted with ethyl acetate (3 x 100 cc), the solvent is evaporated on a water bath and the residue is recrystallized from heptane (150 cc). 3(9,9-dioxy-10-phenthiazinyl)-2-methyl-1-dimethylaminopropane (78 g) is obtained, MP 115°C.
The corresponding hydrochloride prepared in ethyl acetate and recrystallized from a mixture of ethanol and isopropanol melts at 250°C.

Therapeutic Function

Antihistaminic

OXOMEMAZINE Preparation Products And Raw materials

OXOMEMAZINE Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
Shijiazhuang Gantuo Biotechnology Co., Ltd
+8613373514458 gantuo02@cngantuo.com China 218 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Alfa Chemistry
+1-5166625404 Info@alfa-chemistry.com United States 21317 58
Shaanxi Didu New Materials Co. Ltd
+86-89586680 +86-13289823923 1026@dideu.com China 9020 58
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 50000 58
Hebei Miaoyin Technology Co.,Ltd
+86-17367732028 +86-17367732028 kathy@hbyinsheng.com China 3582 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58

View Lastest Price from OXOMEMAZINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-06-26 Oxomemazine
3689-50-7
US $200.00 / kg 1kg 99% 1000kg/Month Hebei Mingeng Biotechnology Co., Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-04-11 Oxomemazine
3689-50-7
US $100.00 / g 10g 99% 1000g Shijiazhuang Gantuo Biotechnology Co., Ltd
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • Oxomemazine
    3689-50-7
  • US $200.00 / kg
  • 99%
  • Hebei Mingeng Biotechnology Co., Ltd
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • Oxomemazine
    3689-50-7
  • US $100.00 / g
  • 99%
  • Shijiazhuang Gantuo Biotechnology Co., Ltd

OXOMEMAZINE Spectrum

OXOMEMAZINE 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine-5,5-dioxide 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl-, 5,5-dioxide 3-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N,2-trimethyl-1-propanamine 6487 RP 6847 R.P. 6847 RP Alimemazine S,S-dioxide Dosegran Doxergan Dysedon Imakol Oxomemazin Oxymemazine Phenothiazine, 10-[3-(dimethylamino)-2-methylpropyl]-, 5,5-dioxide RP-6847 S,S-Dioxo-9,9-(dimethylamino-3-methyl-2-propyl)-10-phenothiazine Trimeprazine 5,5-dioxide Oxomemazinebase Oxomenazine OXOEMAZINE 10-(3-Dimethylamino-2-methylpropyl)-10H-phenothiazine 5,5-dioxide 10-[2-(Dimethylaminomethyl)propyl]-10H-phenothiazine 5,5-dioxide N,N,β-Trimethyl-10H-phenothiazine-10-propan-1-amine 5,5-dioxide [3-(5,5-diketophenothiazin-10-yl)-2-methyl-propyl]-dimethyl-amine 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethyl-propan-1-amine 3-(5,5-dioxophenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine 10H-Phenothiazine-10-propanamine, N,N,β-trimethyl-, 5,5-dioxide OxomemazineQ: What is Oxomemazine Q: What is the CAS Number of Oxomemazine Q: What is the storage condition of Oxomemazine Q: What are the applications of Oxomemazine histamine H1-receptor,OXOMEMAZINE,Histamine Receptor,inhibit,phenothiazine,antimuscarinic,muscarinic M1,Inhibitor,Metabotropic glutamate receptors,cough,anticholinergic,antihistamine,mGluR 3689-50-7
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