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ChemicalBook >> CAS DataBase List >> Telmisartan

Telmisartan

trực tiếp đá gà hôm nayLiên kết đăng nhập
  • $5 - $1200
  • Product name: Telmisartan
  • CAS: 144701-48-4
  • MF: C33H30N4O2
  • MW: 514.62
  • EINECS:620-494-7
  • MDL Number:MFCD00918125
  • Synonyms:2-[4-[[4-methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl]methyl]phenyl]benzoic acid;2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propyl-benzimidazol-1-yl]methyl]phenyl]benzoic acid;2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid;4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimidazol-3'-yl)methyl]biphenyl-2-carboxylic acid;Telmisartan Synonyms 4'[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl][1,1'-biphenyl]-2-carboxylic acid;4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-;4'-[{1,4'-Dimethyl-2'-Propyl[2,6'-Bi-1H-Benzimiaszol]-1'yl}-Methyl}-1,1'-Biphenyl-2-Caroxylic Acid Dimethyl Ethyl Ester;4'-[{1,4'-Dimethyl-2'-Propyl[2,6'-Bi-1H-Benzimiaszol]-1'yl}-Methyl}-1,1'-Biphenyl-2-Caroxylic Acid
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Brand

  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological

Package

  • y0001003
  • y0000649
  • 500mg
  • 25mg
  • 200mg
  • y0000648
  • 10
  • 50mg
  • 100mg
  • 1g
  • 10mg
  • 250mg
  • 50
  • 2.5g
  • 5g
  • 10g
  • 25g
  • 500g
  • 100g
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0460-M010
  • Product descriptionTelmisartan ≥98%(HPLC)
  • Packaging10mg
  • Price$29
  • Updated2022-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0460-M050
  • Product descriptionTelmisartan ≥98%(HPLC)
  • Packaging50mg
  • Price$88
  • Updated2022-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1573
  • Product descriptionTelmisartan 98%
  • Packaging1g
  • Price$360
  • Updated2022-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF352
  • Product descriptionTelmisartan
  • Packaging1g
  • Price$14
  • Updated2022-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF352
  • Product descriptionTelmisartan
  • Packaging25g
  • Price$87
  • Updated2022-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61441
  • Product descriptionTelmisartan, 99%
  • Packaging250mg
  • Price$69.8
  • Updated2024-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61441
  • Product descriptionTelmisartan, 99%
  • Packaging1g
  • Price$191
  • Updated2024-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging100mg
  • Price$5
  • Updated2022-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging1g
  • Price$6
  • Updated2022-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging5g
  • Price$8
  • Updated2022-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging10g
  • Price$15
  • Updated2022-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging25g
  • Price$28
  • Updated2022-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging100g
  • Price$102
  • Updated2022-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA219723
  • Product description4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+%
  • Packaging500g
  • Price$496
  • Updated2022-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8531
  • Product descriptionTelmisattan
  • Packaging50mg
  • Price$50
  • Updated2022-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8531
  • Product descriptionTelmisattan
  • Packaging10mM(in 1mL DMSO)
  • Price$65
  • Updated2022-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-T0460-M010 Telmisartan ≥98%(HPLC) 10mg $29 2022-12-16 Buy
Adipogen Life Sciences CDX-T0460-M050 Telmisartan ≥98%(HPLC) 50mg $88 2022-12-16 Buy
AHH API-1573 Telmisartan 98% 1g $360 2022-12-16 Buy
AK Scientific F352 Telmisartan 1g $14 2022-12-16 Buy
AK Scientific F352 Telmisartan 25g $87 2022-12-16 Buy
Alfa Aesar J61441 Telmisartan, 99% 250mg $69.8 2024-06-20 Buy
Alfa Aesar J61441 Telmisartan, 99% 1g $191 2024-06-20 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 100mg $5 2022-12-16 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 1g $6 2022-12-16 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 5g $8 2022-12-16 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 10g $15 2022-12-16 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 25g $28 2022-12-16 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 100g $102 2022-12-16 Buy
Ambeed A219723 4'-((1,7'-Dimethyl-2'-propyl-1H,3'H-[2,5'-bibenzo[d]imidazol]-3'-yl)methyl)-[1,1'-biphenyl]-2-carboxylicacid 99+% 500g $496 2022-12-16 Buy
ApexBio Technology A8531 Telmisattan 50mg $50 2022-12-16 Buy
ApexBio Technology A8531 Telmisattan 10mM(in 1mL DMSO) $65 2022-12-16 Buy

Properties

Melting point :261-263°C
Boiling point :771.9±70.0 °C(Predicted)
Density :1.16
RTECS :DV2037500
storage temp. :2-8°C
solubility :DMSO: >5 mg/mL at 60 °C
pka :3.86±0.36(Predicted)
form :solid
color :white
Water Solubility :insoluble
Merck :14,9129
BCS Class :2
Stability :Hygroscopic
InChIKey :RMMXLENWKUUMAY-UHFFFAOYSA-N
SMILES :C1(C2=CC=C(CN3C(CCC)=NC4=C(C)C=C(C5N(C)C6=CC=CC=C6N=5)C=C43)C=C2)=CC=CC=C1C(O)=O
CAS DataBase Reference :144701-48-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): trực tiếp đá gà hôm nayLiên kết đăng nhập
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning trực tiếp đá gà hôm nayLiên kết đăng nhập P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning trực tiếp đá gà hôm nayLiên kết đăng nhập P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning trực tiếp đá gà hôm nayLiên kết đăng nhập
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

Angiotensin II is a peptide hormone which regulates blood pressure and fluid balance, contributing to hypertension, atherosclerosis, left ventricular hypertrophy, myocardial infarction, and heart failure. Telmisartan is a nonpeptide angiotensin II receptor antagonist which selectively and insurmountably inhibits the angiotensin II AT1 receptor subtype (Ki = 3.7 nM). It also acts as a partial agonist of PPARγ, activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (EC50 = 4.5 μM). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.

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