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ChemicalBook >> CAS DataBase List >>L-Cystine


Chemical Name:
(H-CYS-OH)2;(CYS)2;l-cystin;-Cystine;1-cystine;Cystine CRS;Cystine acid;L-(-)-CYSTINE;L-CYSTINE BASE;(r-(r*,r*))-3,3’-dithiobis(2-aminopropanoicacid)
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
Last updated:2025-03-27 18:00:30

L-Cystine Properties

Melting point >240 °C (dec.) (lit.)
Boiling point 468.2±45.0 °C(Predicted)
alpha -224 º(c=2 in 1M HCl)
Density 1.68
refractive index -222.5 ° (C=1, 1mol/L HCl)
storage temp. 2-8°C
solubility 1 M HCl: 100 mg/mL
form Powder/Solid
pka 1.0, 2.1, 8.02, 8.71(at 25℃)
color White
optical activity [α]20/D 219±5°, c = 1% in 1 M HCl
Water Solubility 0.112 g/L (25 ºC)
Merck 14,2782
BRN 1728094
Stability Stable. Incompatible with strong oxidizing agents.
LogP 0.773 (est)
CAS DataBase Reference 56-89-3(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS)
NIST Chemistry Reference
EPA Substance Registry System


Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-36-24/25
RIDADR  2811
WGK Germany  3
RTECS  HA2690000
Hazard Note  Irritant
PackingGroup  III
HS Code  29309014
NFPA 704
2 0

L-Cystine price More Price(77)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB1305544 MONOCLONAL ANTI-NEPHRIN antibody produced in mouse clone 174CT2.1.1, crude ascites, buffered aqueous solution 56-89-3 100μL $466 2025-03-01 Buy
Sigma-Aldrich 30200 L-Cystine ≥99.7% (TLC) 56-89-3 25g $43.4 2025-03-01 Buy
Sigma-Aldrich 2470 L-Cystine - CAS 56-89-3 - Calbiochem 56-89-3 25G $77.4 2025-03-01 Buy
Sigma-Aldrich 1161586 Cystine United States Pharmacopeia (USP) Reference Standard 56-89-3 200mg $519 2025-03-01 Buy
Sigma-Aldrich 1.02836 L-Cystine suitable for biopharmaceutical production FCC 56-89-3 1kg $305 2025-03-01 Buy
Product number Packaging Price Buy
SAB1305544 100μL $466 Buy
30200 25g $43.4 Buy
2470 25G $77.4 Buy
1161586 200mg $519 Buy
1.02836 1kg $305 Buy

L-Cystine Chemical Properties,Uses,Production


L-cystine (formula: (SCH2CH(NH2) CO2H)2), the L-form of cystine) is a covalently linked dimeric nonessential amino acid formed through the oxidation of cysteine. It is contained in many foods including eggs, meat, dairy products, and whole grains as well as in skin and hairs. L-cystine and L-methionine are the amino-acids required for wound healing and formation of epithelial tissue. It is able to stimulate the hematopoietic system and promote the formation of white and red blood cells. It can also be used as a component of parental and enteral nutrition. It can also be used for the treatment of dermatitis and protection of liver function. L-cystine is manufactured through the enzymatic conversion from DL-amino thiazoline carboxylic acid.



Chemical Properties

A white or almost white, crystalline powder, practically insoluble in water and in alcohol.


L-Cystine is a non-essential amino acid for human development. L-Cystine is formed by the dimerization of two cysteines through the sulfur.


L-Cystine is used as an antioxidant, protecting tissues against radiation and pollution. It finds application in protein synthesis. It is required for utilization of vitamin B6 and is useful in healing burns and wounds. It is also is required by certain malignant cell lines in the culture medium as well as for the growth of certain micro-organisms. It is useful in the stimulation of hematopoietic system and promotes the formation of white and red blood cells. It is an active ingredient in medications used to treat dermatitis.


L-Cystine has been used in in vitro cystine solubility assay to identify potential drugs that influence cystine solubility. It is also used as a supplement of phosphate-buffered saline to slice and wash periprosthetic tissues.


ChEBI: L-cystine is the L-enantiomer of the sulfur-containing amino acid cystine. It has a role as a flour treatment agent, a human metabolite, a Saccharomyces cerevisiae metabolite, a mouse metabolite and an EC (aspartate-semialdehyde dehydrogenase) inhibitor. It is a cystine, a L-cysteine derivative and a non-proteinogenic L-alpha-amino acid. It is a conjugate acid of a L-cystine anion. It is an enantiomer of a D-cystine. It is a tautomer of a L-cystine zwitterion.

General Description

This Standard Reference Material (SRM) is intended primarily for use in validating microchemical procedures for the determination of carbon, hydrogen, nitrogen, and sulfur in organic matter. SRM 143d is pure crystalline cystine supplied in a 2 g unit size. For more information, please refer to the SDS and COA.

SRM 143D_cert SRM 143D _SDS

Biochem/physiol Actions

Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-cystine is crucial for oxygen production and low density lipoprotein modification by arterial smooth muscle cells. It also has a role in the synthesis of glutathione.

Safety Profile

Low toxicity by ingestion. When heated to decomposition it emits toxic fumes of PO, and SOx

Purification Methods

Cystine disulfoxide impurity is removed by treating an aqueous suspension with H2S. The cystine is filtered off, washed with distilled water and dried at 100o under a vacuum over P2O5. Crystallise it by dissolving in 1.5M HCl, then adjusting to neutral pH with ammonia. Likely impurities are D-cystine, meso-cystine and tyrosine. Also purify it by dissolving it in 10% NH3 and adding gradually dilute AcOH until the point of precipitation and cooling slowly [Dughton & Harrison Acta Cryst 12 396, 402 1959.] Alternatively dissolve it in 6N NH4OH and evaporate it at room temperature for crystallisation to occur. [Chaney & Steinrauf Acta Cryst 30 711 1974, Beilstein 4 IV 3155.]
Synthesis of L-Cystine from Glutathione
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View Lastest Price from L-Cystine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2025-03-27 L-Cystine
US $5.00-0.10 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2025-03-11 L-Cystine
US $35.00-15.00 / kg 500kg 99.9 200tons Shandong Juchuang Chemical Co., LTD
trực tiếp đá gà hôm nayLiên kết đăng nhập 2025-01-08 L-Cystine
US $25.00 / kg 1kg 99.96% 500ton Wuhan Boyuan Import & Export Co., LTD
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • L-Cystine
  • US $5.00-0.10 / KG
  • 98%
  • Henan Fengda Chemical Co., Ltd
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • L-Cystine
  • US $35.00-15.00 / kg
  • 99.9
  • Shandong Juchuang Chemical Co., LTD
  • trực tiếp đá gà hôm nayLiên kết đăng nhập
  • L-Cystine
  • US $25.00 / kg
  • 99.96%
  • Wuhan Boyuan Import & Export Co., LTD
3,3’-dithiobis-l-alanin 3,3'-Dithiobis(2-aminopropanoic acid) 3,3'-Dithiodialanine Alanine, 3,3'-dithiobis- Alanine, 3,3'-dithiodi- alpha-Diamino-beta-dithiolactic acid beta,beta’-diamino-beta,beta’-dicarboxydiethyldisulfide beta,beta’-dithiodialanine beta,beta'-Diamino-beta,beta'-dicarboxydiethyl disulfide beta,beta'-Dithiobisalanine beta,beta'-Dithiodialanine Bis(beta-amino-beta-carboxyethyl) disulfide bis(beta-amino-beta-carboxyethyl)disulfide Cysteine disulfide cysteinedisulfide Cystin cystineacid Dicysteine Gelucystine (L form) L-3,3’-Dithiodialanine Nephrin Oxidized L-cysteine oxidizedl-cysteine Propanoic acid, 3,3'-dithiobis(2-amino-, (R-(R*,R*))- (R)-(-)-CYSTINE (R,R)-(-)-CYSTINE (R,R)-3,3'-DITHIOBIS(2-AMINOPROPIONIC ACID) l-cysteinedisulfide L-Dicystiene BETA,BETA'-DITHIOBIS-A-AMINOPROPIONIC ACID CYSTINE, L- H-L-CYSTINE L(-)-3,3'-DITHIOBIS(2-AMINOPROPANOIC ACID) L-CYSTINE L-CYSTINE extrapure gelucystine L-3, 31-dithiobis (2-aminopropanoic acid) L-Cystinic acid L-β,β'-Dithiobis(2-amino-pro-panoic acid) L-Cystine, Metal binding, protein structure, antioxidant (2R)-2-Amino-3-[(2R)-2-amino-3-hydroxy-3-oxopropyl]disulfanylpropanoic acid L-(-)-3,3'-Dithiobis (2-aminopropionic acid) 3,3'-Dithiobis(L-alanine) (2S,7S)-(-)-Cystine L-CYSTINERESEARCH GRADE L-Cystine, extra pure, FCC L-α-DiaMino-β-dithiolacetic acid L-β,β′-DiaMino-β,β′-dicarboxydiethyl disulfide L-β,β′-Dithiodialanine L-Dicysteine Cystine (200 mg) [R-(R*,R*)]-3,3'-Dithiobis [2-aMinopro Bis(β-aMino-β-carboxyethyl) Disulfide Cystine Αcid NSC 13203 L-CYTISINE 3,3'-DITHIOBIS(2-AMINOPROPIONIC ACID) 2-AMINO-3-[(2-AMINO-2-CARBOXYETHYL)DITHIO]PROPANOIC ACID
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