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Indole-3-carboxylic acid

Chemical Name:
Indole-3-carboxylic acid
1H-INDOLE-3-CARBOXYLIC ACID;ICO;3-Indoleformic acid;e-3-carboxyL;3-Indoleformic;3-CARBOXYINDOLE;3-indoleic acid;3-Indolecarboxylic;Indol-3-carbonsure;Indole-3-carboxylic
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Last updated:2024-08-28 13:27:38

Indole-3-carboxylic acid Properties

Melting point 232-234 °C (dec.)(lit.)
Boiling point 287.44°C (rough estimate)
Density 1.2480 (rough estimate)
refractive index 1.5050 (estimate)
storage temp. 2-8°C
solubility Soluble in 95% Ethanol: 50 mg/ml, also soluble in methanol.
form Powder
pka 3.90±0.10(Predicted)
color Light beige
BRN 129435
CAS DataBase Reference 771-50-6(CAS DataBase Reference)
EWG's Food Scores


Risk and Safety Statements

Symbol(GHS)  trực tiếp đá gà hôm nayLiên kết đăng nhập
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-21/22
Safety Statements  22-24/25-36/37/39-26
WGK Germany  3
RTECS  NK7882892
HazardClass  IRRITANT
HS Code  29339900
NFPA 704
2 1

Indole-3-carboxylic acid price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 284734 Indole-3-carboxylic acid ReagentPlus , 99% 771-50-6 5g $55.8 2025-03-01 Buy
Sigma-Aldrich 284734 Indole-3-carboxylic acid ReagentPlus , 99% 771-50-6 1g $35 2024-06-20 Buy
TCI Chemical I0028 Indole-3-carboxylic Acid >98.0%(T)(HPLC) 771-50-6 5g $54 2025-03-01 Buy
TCI Chemical I0028 Indole-3-carboxylic Acid >98.0%(T)(HPLC) 771-50-6 25g $156 2025-03-01 Buy
Alfa Aesar A12634 Indole-3-carboxylic acid, 98% 771-50-6 1g $23.65 2025-03-01 Buy
Product number Packaging Price Buy
284734 5g $55.8 Buy
284734 1g $35 Buy
I0028 5g $54 Buy
I0028 25g $156 Buy
A12634 1g $23.65 Buy

Indole-3-carboxylic acid Chemical Properties,Uses,Production

Chemical Properties

light beige crystalline powder (recrystallized from acetate-petroleum ether). Soluble in ethanol, ether, acetate, insoluble in boiling water, benzene, insoluble in petroleum ether.


Indole-3-carboxylic Acid is a specific and competitive inhibitor of the potentiation of glycine of NMDA-gated current. Chemical reagent in the synthesis of thiadiazole derivatives used for anticancer activity.


indole-3-carboxylic acid can be synthesized by the hydrolysis reaction of 3-trichloroacetyl indole: add 235g 3-trichloroacetyl indole into 1000ml methanol, slowly drop an appropriate amount of 50% KOH solution, heat up and reflux for 18 hours, cool to room temperature, The methanol was recovered by concentration, and the residual liquid was left; 1500 ml of water was added to the residual liquid, hydrochloric acid was added dropwise to adjust pH=3~4, and then filtered, and the solid obtained by filtration was dried to obtain 144g of indole-3-carboxylic acid crude product; The crude product was slurried with 100g of ethyl acetate for 25 minutes,filtered and dried to obtain indole-3-carboxylic acid (137g, yield 91.8%).


ChEBI: Indole-3-carboxylic acid is an indole-3-carboxylic acid carrying a carboxy group at position 3. It has a role as a human metabolite and a bacterial metabolite. It is a conjugate acid of an indole-3-carboxylate.

General Description

The structures of the derivatives of indole-3-carboxylic acid were studied using gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and Fourier transform infrared spectroscopy (FT-IR).


5-HT Receptor
Synthesis of Indole-3-carboxylic acid from Indole-3-carboxaldehyde
Global( 681)Suppliers
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View Lastest Price from Indole-3-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-08-29 3-Indoleformic acid
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
trực tiếp đá gà hôm nayLiên kết đăng nhập 2024-04-01 Indole-3-carboxylic acid
US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
trực tiếp đá gà hôm nayLiên kết đăng nhập 2023-10-19 3-Indoleformic acid
US $30.00 / kg 1kg 99% 100 Hebei Duling International Trade Co. LTD
Indole-3-carboxylic acid ,99% INDOLE-3-CARBOXYLIC ACID(I3CA) INDOLE-3-CARBOXYLIC ACID pure Indole-3-CarboxylicA 1H-Indole-3-carboxylic acid 98% Indole-3-carboxylic Indole-3-carboxylic acid (8CI) Indole-3-carboxylie acid IndolecarboxylicAcid INDOLECARBOXYLIC ACID 98% 3-Indoleformic Indole-3-carboxylic acid, 99% 1GR INDOLE-3-CARBOXYLIC ACID FOR SYNTHESIS 3-Carboxy-1H-indole Indole-3-carboxylic acid, refined Indole-3-carboxylic acid ReagentPlus(R), 99% β-Indolylcarboxylic acid Indole-3-carboxylic acid Vetec(TM) reagent grade, 98% TIMTEC-BB SBB003952 RARECHEM AL BO 0353 3-INDOLYLCARBOXYLIC ACID 3-INDOLECARBOXYLIC ACID 3-CARBOXYINDOLE INDOLE-3-CARBOXYLIC ACID e-3-carboxyL Indole-3-carboxylic acid, 99%, refined Indole-3-carboxylic acid 3-Indoleformic acid in stock Factory Tropisetron Hydrochloride ImpuritⅠ:3-Indoleformic acid Tropisetron impurity B CRS Indole-3-carboxylicAcid> Tropisetron EP Impurity B Tropisetron Impurity 2 (Tropisetron EP Impurity B) Tropisetron hydrochloride EP Impurity B 3-Indolecarboxylic Tropisetron Hydrochloride ImpuritⅠ:3-Indoleformic acid 1H-INDOLE-3-CARBOXYLIC ACID ICO 3-Indoleformic acid Indol-3-carbonsure 2H5]-Indole-3-carboxylic Acid Indok-3-Carboxylic acid 1H-Indol-3-carboxylic acid 3-indoleic acid 771-50-6 C9H6O2N C9H6NO2 Simple Indoles Indoles Heterocyclic Building Blocks Building Blocks Simple Indoles Carboxylic Acids Pyrroles & Indoles Building Blocks Heterocyclic Building Blocks Indoles Indoles and derivatives IndoleDerivative
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