| Identification | Back Directory | [Name]
D-ERYTHRO-C20-DIHYDROSPHINGOSINE | [CAS]
24006-62-0 | [Synonyms]
C20 sphinganine
Sphinganine-C20
Sphinganine (d20:0)
D-ERYTHRO-SPHINGANINE, C20 CHAIN
D-ERYTHRO-C20-DIHYDROSPHINGOSINE
D-erythro-sphinganine (C20 base)
1,3-Eicosanediol, 2-amino-, (2S,3R)-
D-ERYTHRO-SPHINGANINE (C20 BASE);SPHINGANINE (D20:0) | [Molecular Formula]
C20H43NO2 | [MDL Number]
MFCD08703033 | [MOL File]
24006-62-0.mol | [Molecular Weight]
329.56 |
| Chemical Properties | Back Directory | [Boiling point ]
471.9±25.0 °C(Predicted) | [density ]
0.920±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Chloroform:Methanol (5:1): soluble; Ethanol: soluble, warmed | [form ]
A solid | [pka]
12.57±0.45(Predicted) |
| Hazard Information | Back Directory | [Description]
Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); ) that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well as in some cancers. Sphinganine can block protein kinase C activation in some cases but not others. [Matreya, LLC. Catalog No. 1845] | [Uses]
Sphinganine-C20 is a sphingolipid that plays an important role in the regulation of central cellular processes, including cell growth, survival and differentiation. | [Definition]
ChEBI: A 2-aminoicosane-1,3-diol having (2S,3R)-configuration. |
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