Identification | Back Directory | [Name]
Tigecycline (open C-ring D-ring) Quinone | [CAS]
1268494-46-7 | [Synonyms]
Tigecycline Impurity 4 Tigecycline Impurity 9 Tigecycline USP Impurity F Tigecycline Quinone Impurity Tigecycline Quinone Analogue (S)-4-((6-(2-(tert-butylamino)acetamido) Tigecycline (open C-ring D-ring) Quinone Tigecycline Impurity 2(Tigecycline quinone analog) Tigecycline (open C-ring D-ring) Quinone (Technical Grade)
DISCONTINUED. Please see T440035 4-[[(2S)-6-[[2-(tert-butylamino)acetyl]amino]-8-(dimethylamino)-5-hydroxy-4-oxo-2,3-dihydro-1H-naphthalen-2-yl]methyl]-2,5-dihydroxy-3,6-dioxocyclohexa-1,4-diene-1-carboxamide 1,4-Cyclohexadiene-1-carboxamide, 4-[[(2S)-8-(dimethylamino)-6-[[2-[(1,1-dimethylethyl)amino]acetyl]amino]-1,2,3,4-tetrahydro-5-hydroxy-4-oxo-2-naphthalenyl]methyl]-2,5-dihydroxy-3,6-dioxo- | [Molecular Formula]
C26H32N4O8 | [MOL File]
1268494-46-7.mol | [Molecular Weight]
528.55 |
Chemical Properties | Back Directory | [Melting point ]
>148°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Dark Red |
Hazard Information | Back Directory | [Uses]
Tigecycline (open C-ring D-ring) quinone is an impurity of Tigecycline (T440015), one of the very few glycylcycline antimicrobials that exhibit activity against Gram-negative bacteria and also one of the few that also circumvent around the major resistance mechanisms of tetracycline. |
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